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Immune Thrombocytopenia (ITP) Epidemiology Forecast, Diagnosis, Treatment Options | DelveInsight

DelveInsight’s Immune Thrombocytopenia (ITP) Epidemiology Forecast–2030’ report delivers an in-depth understanding of the ITP, historical and forecasted epidemiology as well as the ITP trends in the United States, EU5 (Germany, France, Italy, Spain, and the United Kingdom) and Japan.

Some Key facts of the Report

  • Assessments as per DelveInsight’s analysts show that the majority of cases of ITP are females as compared to males. There was a total of 32,364 female and 20,998 male diagnosed cases of ITP in 2017 in the United States.
  • DelveInsight’s estimations suggest that the total prevalent population ITP in the seven major markets was approximately 180,498 in 2017.
  • The total diagnosed prevalent cases in the 7MM was estimated to be approximately 147,174 in 2017.
  • In 2017, there were around 63,725 prevalent cases and approximately 53,362 diagnosed prevalent cases of ITP in the United States. Out of the total diagnosed cases, approximately 49,640 cases account for adult ITP and approximately 3,723 cases were diagnosed prevalence population in children in 2017 in the United States.
  • Japan had 27,005 prevalent cases of ITP in 2017.
  • Among the European countries, the United Kingdom had the highest prevalent population of ITP with approximately 26,274 cases, followed by Italy which had a prevalent population of approximately 18,604 in 2017. On the other hand, Spain had the lowest prevalent population of approximately 12,207 cases in 2017.

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Immune Thrombocytopenia (ITP), previously called immune thrombocytopenic purpura or idiopathic thrombocytopenic purpura, is an autoimmune disorder that occurs when the body attacks its platelets and destroys them too quickly. ITP is a disorder that affects the overall number of blood platelets rather than their function. Many of the symptoms of ITP stem from a low platelet count leading to excessive bleeding. In severe cases, frequent bleeding episodes may result in low levels of circulating red blood cells (anemia), which may cause fatigue and impair response to exertion. In rare cases, serious bleeding into the brain (intracranial hemorrhage) may occur.

The two main types of ITP are acute (short term) and chronic (long term). ITP is also categorized as primary and secondary based on the cause of the disease. ITP in the absence of other causes or disorders that may be associated with the thrombocytopenia is known as primary ITP, whereas, secondary ITP refers to immune-mediated thrombocytopenia with an underlying cause, including drug-induced, or associated with systemic illness (e.g., systemic lupus erythematosus, infection [e.g., HIV], immune deficiency [e.g., common variable immunodeficiency or autoimmune lymphoproliferative syndrome], and other causes).

Immune Thrombocytopenia (ITP) Epidemiology Perspective by DelveInsight

The disease epidemiology covered in the report provides historical as well as forecasted epidemiology segmented by Total Prevalent Population of ITP, Total Diagnosed Prevalent Population of ITP, and Gender-specific Diagnosed Prevalent Population of ITP scenario of ITP in the 7MM covering the United States, EU5 countries (Germany, France, Italy, Spain, and the United Kingdom) and Japan from 2017 to 2030.

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Scope of the Report

  • The report covers the descriptive overview of ITP, explaining its causes, signs and symptoms, and pathophysiology.
  • The report provides insight into the 7MM historical and forecasted patient pool covering the United States, EU5 countries (Germany, France, Italy, Spain, and the United Kingdom) and Japan.
  • The report assesses the disease risk and burden and highlights the unmet needs of ITP.
  • The report helps to recognize the growth opportunities in the 7MM with respect to the patient population.
  • The report provides the segmentation of the disease epidemiology for 7MM by Total Prevalent Population of ITP, Total Diagnosed Prevalent Population of ITP, and Gender-specific Diagnosed Prevalent Population of ITP.

Report Highlights

  • 11-Year Forecast of ITP
  • 7MM Coverage
  • Total Prevalent Population of ITP
  • Total Diagnosed Prevalent Population of ITP

Gender-specific Diagnosed Prevalent Population of ITP

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Table of Contents

1. Key Insights

2. Executive Summary of Immune Thrombocytopenia

3. SWOT Analysis for Immune Thrombocytopenia

4. Immune Thrombocytopenia (ITP) Epidemiology Overview at a Glance

4.1. Epidemiology Share (%) Distribution of Immune Thrombocytopenia (ITP) in 2017

4.2. Epidemiology Share (%) Distribution of Immune Thrombocytopenia (ITP) in 2030

5. Immune Thrombocytopenia (ITP): Disease Background and Overview

5.1. Introduction

5.2. Etiology of Immune Thrombocytopenia (ITP)

5.3. Signs and Symptoms of Immune Thrombocytopenia (ITP)

5.4. Types of Immune Thrombocytopenia (ITP)

5.5. Pathophysiology of Immune Thrombocytopenia (ITP)

5.6. Pathogenesis of Immune Thrombocytopenia (ITP)

5.7. Genetic background and environmental factors related to ITP

5.8. Biomarkers associated with Immune Thrombocytopenia (ITP)

5.9. Diagnosis of Immune Thrombocytopenia

5.10. Diagnostic Guidelines of Immune Thrombocytopenia

5.10.1. 2011 Clinical Practice Guideline on the Evaluation and Management of Immune Thrombocytopenia (ITP)

5.10.2. The American Society of Hematology 2011 evidence-based practice guideline for Immune Thrombocytopenia

5.10.3. Japanese practice guidelines for newly diagnosed childhood idiopathic thrombocytopenic purpura

5.10.4. Spanish Society of Hematology and Hemotherapy: Guidelines for diagnosis, treatment and monitoring of the PTI

6. Epidemiology and Patient Population

6.1. Key Findings

6.2. 7MM Total Prevalent Patient Population of Immune Thrombocytopenia (ITP)

6.3. 7MM Diagnosed Prevalent Patient Population of Immune Thrombocytopenia

7. Country Wise-Epidemiology of Immune Thrombocytopenia (ITP)

7.1. United States Epidemiology

7.1.1. Assumptions and Rationale

7.1.2. Total Prevalent Cases of Immune Thrombocytopenia (ITP) in the United States

7.1.3. Diagnosed Prevalence of Immune Thrombocytopenia in the United States

7.1.4. Gender-specific Diagnosed Prevalence of Immune Thrombocytopenia in the United States

7.2. EU5 Epidemiology

7.2.1. Germany

7.2.1.1. Assumptions and Rationale

7.2.1.2. Total Prevalent Cases of Immune Thrombocytopenia (ITP) in Germany

7.2.1.3. Diagnosed Prevalence of Immune Thrombocytopenia in Germany

7.2.1.4. Gender-specific Diagnosed Prevalence of Immune Thrombocytopenia in Germany

7.2.2. France

7.2.2.1. Assumptions and Rationale

7.2.2.2. Total Prevalent Cases of Immune Thrombocytopenia (ITP) in France

7.2.2.3. Diagnosed Prevalence of Immune Thrombocytopenia (ITP) in France

7.2.2.4. Gender-specific Diagnosed Prevalence of Immune Thrombocytopenia (ITP) in France

7.2.3. Italy

7.2.3.1. Assumptions and Rationale

7.2.3.2. Total Prevalent Cases of Immune Thrombocytopenia in Italy

7.2.3.3. Diagnosed Prevalence of Immune Thrombocytopenia in Italy

7.2.3.4. Gender-specific Diagnosed Prevalence of Immune Thrombocytopenia in Italy

7.2.4. Spain

7.2.4.1. Assumptions and Rationale

7.2.4.2. Total Prevalent Cases of Immune Thrombocytopenia (ITP) in Spain

7.2.4.3. Diagnosed Prevalence of Immune Thrombocytopenia in Spain

7.2.4.4. Gender-specific Diagnosed Prevalence of Immune Thrombocytopenia (ITP) in Spain

7.2.5. United Kingdom

7.2.5.1. Assumptions and Rationale

7.2.5.2. Total Prevalent Cases of Immune Thrombocytopenia (ITP) in the United Kingdom

7.2.5.3. Diagnosed Prevalence of Immune Thrombocytopenia (ITP) in the United Kingdom

7.2.5.4. Gender-specific Diagnosed Prevalence of Immune Thrombocytopenia (ITP) in the United Kingdom

7.3. Japan Epidemiology

7.3.1. Assumptions and Rationale

7.3.2. Total Prevalent Cases of Immune Thrombocytopenia (ITP) in Japan

7.3.3. Diagnosed Prevalence of Immune Thrombocytopenia in Japan

7.3.4. Gender-specific Diagnosed Prevalence of Immune Thrombocytopenia in Japan

8. Appendix

8.1. Report Methodology

9. DelveInsight Capabilities

10. Disclaimer

11. About DelveInsight

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